Side Effects


Injection-site reactions are common

See information on LUCENTIS side effects below.

Serious side effects include infections inside of the eye, cataracts and detached retinas that may cause:

  • Blurry vision
  • Light sensitivity
  • Cloudy vision

Some patients have had increased eye pressure before and within 1 hour of an injection.

Contact or visit your doctor if you experience the symptoms above. 

Uncommonly, LUCENTIS patients have had serious, sometimes fatal, problems related to blood clots, such as heart attacks or strokes. Although there were only few fatal events which included causes of death typical of patients with advanced diabetic complications, these events may be caused by LUCENTIS.

The most common eye-related side effects are:

  • Increased redness in the white part of the eye
  • Eye pain that can feel like throbbing, itching, or soreness
  • Eye floaters, or small string-like objects or dots that appear to float around your line of vision
  • Increased eye pressure that can make it difficult to open or close eyes. It can also feel like a throbbing sensation behind your eye

The most common non–eye-related side effects are:

  • Nose infections that may cause sneezing, runny nose, or bleeding
  • Throat infections that may cause coughing
  • Anemia that may cause tiredness and fatigue
See the LUCENTIS Important Safety Information below for more information on side effects and the LUCENTIS Full Prescribing Information.
Financial Assistance Options

Financial Assistance Options

There may be options to help you afford LUCENTIS, no matter what type of health insurance you have. Learn about Genentech Ophthalmology Access Solutions.

Important Safety Information & Indication

Who is LUCENTIS for? LUCENTIS® (ranibizumab injection) is a prescription medicine for the treatment of patients with macular edema following retinal vein occlusion (RVO).

What important safety information should I know about LUCENTIS? You should not use LUCENTIS if you have an infection in or around the eye or are allergic to LUCENTIS or any of its ingredients. LUCENTIS is a prescription medication given by injection into the eye, and it has side effects. Some LUCENTIS patients have had detached retinas and serious eye infections. If your eye becomes red, sensitive to light, or painful, or if you have a change in vision, call or visit your eye doctor right away. 

Some LUCENTIS patients have had increases in eye pressure before and within 1 hour of an injection.

Uncommonly, LUCENTIS patients have had serious, sometimes fatal, problems related to blood clots, such as heart attacks or strokes.

Severe inflammation of vessels in the retina has happened for patients treated with LUCENTIS. Call your healthcare provider immediately if you experience a change in vision.

Some LUCENTIS patients have serious side effects related to the injection. These include serious infections inside the eye, detached retinas, and cataracts. The most common eye-related side effects are increased redness in the white of the eye, eye pain, small specks in vision, and increased eye pressure. The most common non–eye-related side effects are nose and throat infections, anemia, nausea and cough. Ask your doctor if you have questions or want more information.

You may report side effects to the FDA at (800) FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at (888) 835-2555.

For additional Safety Information, please talk to your doctor and see the LUCENTIS full Prescribing Information.